Here are the games that acquired the most new players between Thanksgiving 2010 and Thanksgiving 2011, ranked by the number of players (*minus 500 if the game is showing up for the first time as having more than 500 players ever).
7 Wonders is pretty clearly the de facto game of the year. The others are a nice mix of new games and evergreen titles, all worth considering as Christmas gifts.
6605 7 Wonders 2652 Dominion 2421 Forbidden Island 2162* Resistance 2131 Carcassonne 2127 Agricola 2093 Dixit 2084 Alien Frontiers 2057 Small World 2019* Sid Meier's Civilization: The Board Game 1960 Dominant Species 1945* Troyes 1921 Pandemic 1890* Quarriors! 1874 Settlers of Catan 1734 Puerto Rico 1700 Stone Age 1676 London 1655 Glen More 1641 Power Grid 1631 Race for the Galaxy 1609 Survive: Escape from Atlantis! 1596 Innovation 1583 Ticket to Ride 1525* Mansions of Madness 1521 Citadels